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PCOS is the Prime Cause of Infertility in Women in India, New Study Says


Infertility is becoming a global issue subjective to social, psychological, and physical implications. In India, the prevalence of infertility has been high for 40 years now. With a growing urban population, polycystic ovarian/ovary syndrome (PCOS) has been profoundly affecting fertility in reproductive-aged women. 

A recent, comprehensive, population-based study of 100 female participants from an urban group between  18-40 years with distinct primary and secondary infertility conditions depicted PCOS as the most common cause of female infertility.

Also Read: Women with Undiagnosed Endometriosis Face Difficulty in Getting Pregnant, Research Says

According to the statistical study, as many as 50 urban women showed menstrual abnormalities such as delayed, irregular, or absence of menstruation or even heavy menstrual flow, while the other 50 had normal menstruation patterns. 

The indicative results of the survey;

  • The majority of women (50%) had ovarian factors as the main culprit of infertility, and nearly 23.04% among them showed PCOS as the chief infertility causing ovarian factor.
  • This was followed by tubal factors (22%) with bilateral tubal blockage (12.86%) as the most common tubal pathology detected. 
  • The next was uterine factor (20%), among which nearly 20.8% of the women contributed to Mullerian tract anomaly (20.8%).
  • Lastly, 19% of the women showed peritoneal factors while other female fertility factors such as endocrine factors and pelvic factors were also considered accounting for more lesser numbers. 

The conclusive results of primary fertility (62%) is more concerning than women having secondary infertility (38%) issues. Owing to sedentary lifestyle, lesser physical activity, poor nutritional habits in urban population, ovarian factors lead the way of major infertility causing factors in women with PCOS as the prime fertility factor of both primary and secondary infertility. 

This study used data presented by Department of Obstetrics and Gynaecology, South central Railway Hospital, Secunderabad; Department of PSM, LTMMC and GH, Sion, Mumbai

The paper is published in the International Journal of Reproduction, Contraception, Obstetrics and Gynaecology, JUNE 2021. DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20212340 

Pooja N Swamy (M.Sc Biomedical Sciences)
Pooja Holds Master's Degree in Biomedical Sciences from Vellore Institute of Technology. She believes in strong research and clear understanding over the subject. Always determined and focussed with a thirst to learn new things. Hardworking, flexible and grounded to align with the goals.


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